Using the right concrete sealer depends on first where you plan on using it (either interior or exterior) and what you hope to accomplish by putting it on. Maybe some random person told you, "Hey, you better put a sealer on that" or maybe it's just starting to click in your head that it would be a good idea to protect that large and hard investment of yours.
Some sealers are meant to be used on exterior applications and others are only for use on indoor surfaces. Check with your local distributor of concrete products to find out which type of product will work best for the area that you want to protect.
Here's a word of caution when using an acrylic sealer - do not use it indoors!. The vapors from this sealer are highly explosive! If you insist on using it on a interior surface, make sure there are no open flames anywhere. Be sure and check for piliot lights from gas water heaters, gas furnaces, gas stoves . . . and definatly do not smoke when using these products (no cigarette is worth blowing-up your or someone else's home) - you could seriouly injure or kill yourself (or someone else) in a huge fireball explosion - it's happened before!
One of the benefits of acrylic sealers are that they're pretty easy to apply. Just dip and roll it right out of the bucket or you could spray it with a good pump-up pressure sprayer (one that works with solvent based products). Also, this type of concrete sealer is UV stable (meaning it's protected against Ultra Violet rays) - if you have a beautiful textured surface, stamped concrete or even a broomed finish surface, you don't want it to turn yellow a few months after applying the sealer!
Penetrating sealers are perfect when you want to inexpensively protect an existing concrete slab (like your driveway). These types of sealers penetrate down into the capillaries (just under the surface) of the concrete and form the seal there. No need to worry about the concrete changing color and getting a bit darker like it does with a solvent-based acrylic sealer and there is no need to worry about the surface getting slippery like it might with an acrylic sealer (you should use an anti-slip aggregate between sealer coats for skid resistance if you're going the acrylic sealer route).
On an interior surface, you've got several options. The products that you'll be using inside can be considered more of a (thicker) coating compared to a thin sealer. Clear (or colored) epoxies are what you would want to utilize and although they are extremely durable, they are prone to scratch and scuff marks. So, after your epoxy coating is dry, you are going to have to top-coat it with either a polyurethane or some type of floor wax to protect it from scratching.
Other great protective products for interior uses are polyaspartic sealers. The advantages of a polyaspartic is that it is very quick to dry comparted to epoxies and urethanes and is more UV stable. If drying time is an issue, then I would suggest that you look into a polyaspartic concrete sealer.